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| Pharmaceutical Intermediate |
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Synonyms |
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Disodium 3-amino-1-hydroxy-propylidenebisphosphonate |
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CAS No. |
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109552-15-0 |
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Structure |
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Specification |
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Appearance White or almost white, crystalline powder.
Solubility Soluble in water and in 2M sodium hydroxide; Sparingly soluble in 0.1M hydrochloric acid;
Practically insoluble in organic solvents.
Idmentification A. IR spectrum is concordant with RS
B. A 5% w/v solution yield reactioncharacteristic of sodium salts.
pH 7.8~8.8
Clarity and colour of solution A 2.0% w/v solution is clear and not more intensely Coloured than reference solution Y6
Heavy metals ,ppm 10 Max.
ß-Alanine ,% 0.5Max.
Phosphate,% 0.5Max.
Phosphite,% 0.5Max.
Water(KF) 23.0%-27.0%
Assay NLT98%&NMT102.0%(anhydrous substance) |
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Application |
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Applied as Pharmaceutical Intermediate |
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Remaks |
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